March 22nd, 2011
Osteoarthritis Cartilage. 2011 Jan 4. [Epub ahead of print]
Canine Hip Dysplasia is Predictable by Genotyping.
Guo G, Zhou Z, Wang Y, Zhao K, Zhu L, Lust G, Hunter L, Friedenberg S, Li J, Zhang Y, Harris S, Jones P, Sandler J, Krotscheck U, Todhunter R, Zhang Z.
Abstract
OBJECTIVE: To establish a predictive method using whole nome
genotyping for early intervention in canine hip dysplasia (CHD) risk
management, for the prevention of the progression of secondary
osteoarthritis (OA), and for selective breeding. Continue reading Predictors of Hip Dysplasia
September 6th, 2010
Essays for the dog breeder.
Follow these links to great book chapters on breeding and genetics by Dr. Thorpe-Vargas
Introduction: Dog breeding moves to the next level
Chapter 1: Extraordinary diversity
Chapter 2: A genetics primer
Chapter 3: What you get is not necessarily what you see!
Chapter 4: Ethics and breeding strategies
Chapter 5: The shallow end of the gene pool
Chapter 6: . . . → Read More: Genetics & Breeding strategies
July 3rd, 2010
A must read presentation from the 2010 WSAVA Congress by Jerold S. Bell, DVM (North Grafton, MA, USA) including the following topics:
Introduction
Genetic Tests
Genetic Counseling for Owners
Genetic Counseling for Breeders
Autosomal Recessive Disorders
Autosomal Dominant Disorders
Sex-Linked Disorders
Polygenic Disorders/Complex Inheritance
CLICK . . . → Read More: Genetic Testing and Genetic Counseling in Pet and Breeding Dogs
June 23rd, 2010
http://www.medicalnewstoday.com/articles/192574.php
Michigan State University veterinarians are taking part in a two-year, $5.3 million project to analyze five cancers in dogs, research that could offer new insight into canine cancer genes and their potential impact on the human form of the disease.
“Because purebred dogs have been selected to have specific physical and behavioral traits, their background genetics, within breeds, are very similar, with that ‘background noise’ suppressed, cancer genes are made more obvious.”Barbara Kitchell, director of MSU’s Center for Comparative Oncology said. Continue reading Study Looks At Canine Cancer Genes
May 2nd, 2010
Canine Genetics Primer & FREE Canine Genetics Software
- Free program for predicting phenotypes of dogs based on known genotypes, and calculating mating predictions. From the makers of Breeders Assistant . . . → Read More: Free Canine Genetics Software
June 26th, 2009
From Victoria, Australia
Department of Primary Industries 2009
Breeding programs must consider the effects and ethics of high risk mating combinations that may, based on the principles of genetic inheritance, in theory produce animals with heritable disease. Where such heritable disease has potential to cause severe welfare issues for affected progeny such breeding programs must be justifiable. Affected progeny must be assessed and humanely destroyed if they suffer. Such animals must not be used for breeding. Continue reading Code of practice ; breeding animals
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