Osteoarthritis Cartilage. 2011 Jan 4. [Epub ahead of print]
Canine Hip Dysplasia is Predictable by Genotyping.
Guo G, Zhou Z, Wang Y, Zhao K, Zhu L, Lust G, Hunter L, Friedenberg S, Li J, Zhang Y, Harris S, Jones P, Sandler J, Krotscheck U, Todhunter R, Zhang Z.
Abstract
OBJECTIVE: To establish a predictive method using whole nome
genotyping for early intervention in canine hip dysplasia (CHD) risk
management, for the prevention of the progression of secondary
osteoarthritis (OA), and for selective breeding. Continue reading Predictors of Hip Dysplasia
Category: Inherited Disorders
Specific breed risks
Top 10 Breed-Specific risks; PDF file from Ohio State Univ.
See the top 10 problems for a certain breed.
risk.pdf
Vets asked to report Cesarean Operations
25 Nov 2010
Veterinary associations are asking vets to start reporting cesarean operations to the Kennel Club in the new year as part of the profession’s commitment to improving dog health and welfare. Continue reading Vets asked to report Cesarean Operations
Genetics & Breeding strategies
Essays for the dog breeder.
Follow these links to great book chapters on breeding and genetics by Dr. Thorpe-Vargas
- Introduction: Dog breeding moves to the next level
- Chapter 1: Extraordinary diversity
- Chapter 2: A genetics primer
- Chapter 3: What you get is not necessarily what you see!
- Chapter 4: Ethics and breeding strategies
- Chapter 5: The shallow end of the gene pool
- Chapter 6: Cancer, immune problems and vaccinations
- Chapter 7: And what of the future…?
- Appendix 1: Mapping out the dog’s genetic future
- Appendix 2: Glossary
- Appendix 3
Genetic Testing and Genetic Counseling in Pet and Breeding Dogs
A must read presentation from the 2010 WSAVA Congress by Jerold S. Bell, DVM (North Grafton, MA, USA) including the following topics:
Introduction
Genetic Tests
Genetic Counseling for Owners
Genetic Counseling for Breeders
Autosomal Recessive Disorders
Autosomal Dominant Disorders
Sex-Linked Disorders
Polygenic Disorders/Complex Inheritance
CLICK FOR ARTICLE
Inherited Diseases in Dogs : Cambridge University
This web site contains a guide to diseases/conditions of pure bred dogs which are likely to be transmitted wholly or partly through a genetic mechanism.
* Search the Inherited Diseases in Dogs Database
The site is not designed as a diagnostic system, and I cannot offer individual veterinary advice. If you suspect that your dog is suffering from one of these conditions, contact your veterinarian. The information in the site is correct to the best of my knowledge and belief, but it is necessarily incomplete, and I can give no warranty of accuracy, express or implied. I would be grateful for any corrections, and in particular for information on conditions or references omitted. Please email me with information.
The Inherited Diseases in Dogs Database is compiled by David Sargan. Publications referring to this site should cite Sargan, D.R. IDID: inherited diseases in dogs: web-based information for canine inherited disease genetics. Mamm Genome. 2004 Jun;15(6):503-6.
Study Looks At Canine Cancer Genes
http://www.medicalnewstoday.com/articles/192574.php
Michigan State University veterinarians are taking part in a two-year, $5.3 million project to analyze five cancers in dogs, research that could offer new insight into canine cancer genes and their potential impact on the human form of the disease.
“Because purebred dogs have been selected to have specific physical and behavioral traits, their background genetics, within breeds, are very similar, with that ‘background noise’ suppressed, cancer genes are made more obvious.”Barbara Kitchell, director of MSU’s Center for Comparative Oncology said. Continue reading Study Looks At Canine Cancer Genes